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The anti-inflammatory effects of semaglutide were investigated by analyzing the plasma levels of the inflammatory cytokines TNF- and IFN- in lean C57BL/6J mice challenged with a single dose of LPS
Compounded semaglutide is not the same medication as Wegovy and has not been approved by the FDA
For emergency physicians, this shift matters
Most notably, the FLOW trial, the first dedicated GLP-1 RA kidney outcome trial, demonstrated that once-weekly semaglutide reduced the risk of sustained decline in estimated glomerular filtration rate (eGFR), kidney failure or cardiovascular death in people with CKD and T2D [9]
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