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Class I includes HDAC1, 2, 3, and 8, which are usually localized in the nucleus, have deacetylase activity, and contain zinc-dependent active sites ( + as a cofactor ( Table 1 ) ( Figure 1 ) ( Table 1 Classification of HDACs based on homology to human yeast homologs and generalization of their cofactor, size, and cellular localization

Niacinamide (vitamin B3) works to reduce pigmentation, refine pores, and regulate excess sebum while enhancing the skins barrier function

As a substance, DSIP acts directly on specific cells in the brain and nervous system to exert its diverse effects on central regulatory processes

Glutathione is composed of three non-essential amino acids: cysteine, glycine, and glutamic acid, which serve as fundamental building blocks for proteins