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Effect of siponimod on magnetic resonance imaging measures of neurodegeneration and myelination in secondary progressive multiple sclerosis: Gray matter atrophy and magnetization transfer ratio analyses from the EXPAND phase 3 trial

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The results showed that fluorescence signals from all three suppository formulations were primarily detected within the colorectum over time, with only weak signals observed in major organs, including the heart, liver, spleen, lungs, kidneys, and small intestine

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