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Description

The expression of Cx32 and Cx43 decreased during the H

Physiologically, NO inhibits leukocyteendothelial cell adhesion, VSMC proliferation and migration, and platelet aggregation to maintain the health of the vascular endothelium

These mechanistic actions have been consistently verified in various disease models, including atherosclerosis, intestinal ischemiareperfusion injury (IIRI), and pulmonary ischemiareperfusion injury (LIRI) [341,342,343]