Funding This work was financially supported by the National Natural Science Foundation of China (82160565, 82260565), Jiangxi Province Ganpo Talent Support Program-Key Academic and Technical Leaders in Major Disciplines Project (20232BCJ23035), the Natural Science Foundation of Jiangxi Province (20252BAC200517 and 20252BAC240417), the General Projects of Jiangxi Provincial Department of Education (GJJ2203532), the General Project of Jiangxi Provincial Administration of Traditional Chinese Medicine (2023B1281), the Open Research Fund of Jiangxi Cancer Hospital & Institute (2021J16)
Medical Therapies A number of other agents have been tested in patients with ALD
In multiple organisms, cellular NAD+ levels drop with age, which correlates with the onset of age-related conditions, including metabolic disorders, neurodegeneration, and cardiovascular problems
At the same time, the combination of metformin with other chemotherapy agents or radiotherapy may enhance its anti-tumor effect and provide more options for glioma treatment