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10.1038/s41598-018-25603-5 130 OberheimN

5.2 Mechanisms of Mn neurotoxicity Mn toxicity affects neurotransmitters, neurons, and glial cells through mechanisms that include oxidative stress, inflammation, and apoptosis

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Furthermore, the combined use of these two drugs significantly reduces the glycolipid metabolism levels in tumor cells, including ATP, lactate, acetoacetate, and LDL-C, reshaping the metabolic profile of glioma