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Because knowing what to expect, and what to do when the unexpected happens, is the difference between abandoning a promising protocol and optimizing it for your goals
The 2024 NICE update was explicit on one point: do not rule out B12 deficiency just because the standard blood count looks normal
3.4 Evidence Base Neuropathy Trials : RCTs in diabetic neuropathy show 1,5003,000 mcg methylcobalamin daily improves nerve conduction velocities by up to 20% over 12 weeks
All patients in the study received an initial treatment of 500 g methylcobalamin IM every other day for ten doses followed by 500 g oral methylcobalamin three times a day thereafter
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