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Systemic absorption of tretinoin after topical application is low, and therefore it is unlikely that a significant amount of the drug is excreted into breast milk

Because of its mechanism of action, steatorrhea occurs frequently, limiting the usefulness of this agent

[1] [3] Importantly, patients should seek urgent medical attention if they experience severe or persistent abdominal pain (especially if radiating to the back), repeated vomiting, inability to keep fluids down, signs of dehydration, or jaundice, as these may indicate serious conditions such as pancreatitis or gallbladder disease

Brain endothelial cell junctions after cerebral hemorrhage: Changes, mechanisms and therapeutic targets