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The mechanism of SELENOP intracellular turnover is not fully clear

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Chemistry & Mechanism of Action of Copper Tripeptide (GHK-Cu) The GHK peptide consists of three amino acids, glycine, histidine, and lysine, arranged in a specific sequence that chelates Cu(II) in a square-planar coordination geometry

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However, data obtained from most experiments dealing with in vitro cell exposure to homocysteine are disappointing because the concentrations required are generally high and the effects generally have not been specific to homocysteine (Jacobsen, 1993)

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