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Kumar V, Agarwal S, Saboo B, Makkar B

Aardvark Therapeutics Sector: Oral gut-restricted bitter taste receptor agonists for hunger suppression HQ: San Diego, CA Year Founded: 2017 Origin Story: Aardvark Therapeutics was founded around a mechanistically distinct hypothesis: rather than suppressing appetite like GLP-1 drugs, the companys lead compound activates bitter taste receptors (TAS2Rs) confined to the gastrointestinal tract to trigger local release of satiety hormones, targeting hunger itself without systemic drug exposure

Instead, angle the needle so the water runs down the inside glass wall of the vial

These autonomic nervous systems control the functions that our body does automatically, such as our heartbeat, metabolism, digestion, urinary and bowel movements, and breathing