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Computational approaches for clinical, genomic and proteomic markers of response to glucagon-like peptide-1 therapy in type-2 diabetes mellitus: an exploratory analysis with machine learning algorithms

GLP-1 receptor agonists have now established a role in the type 2 diabetes management algorithm as the preferred second-line agents in patients with known cardiovascular disease, heart failure, or chronic kidney disease, irrespective of baseline HbA1c

140 Whereas the continuous supply of FeS clusters by NFS1 also prevented the iron-starvation response from being triggered in lung adenocarcinomas, NFS1 suppression was shown to predispose cancer cells to ferroptosis