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doi: 10.1016/j.cell.2016.07.004
Initial treatment for B12 deficiency with neurological involvement: When elderly patients present with neurological symptoms (peripheral neuropathy, cognitive impairment, subacute combined degeneration of the cord), urgent and aggressive replacement is essential to prevent irreversible damage
However, the high concentration of GSH within cancer cells is also a major contributor to resistance against conventional therapies such as chemotherapy, radiotherapy, and various dynamic treatments
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