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These are a set of guidelines designed to ensure the quality, consistency, and reliability of non-clinical safety tests, from their inception to the recording and reporting of results

Beyond how much weight the medication is expected to help with, its worth asking what the plan is for preserving muscle and strength during treatment including whether structured movement or strength-focused activity is built into the program rather than left up to the patient alone

Choi JH, Yee SW, Ramirez AH et al (2011) A common 5-UTR variant in MATE2-K is associated with poor response to metformin

Nuklearmedizin 51 (4), 111115