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10.3233/WOR-220581 166 VernonS

While therapeutic dosing generally produces concentrations below 0.5 mol/L, values in people taking recommended dosages have been reported to be very close to the lower limit of APAP-CYS concentration associated with acetaminophen toxic overdoses (1.0 mol/L)

[14] Vessels studied from several archaeological sites in Israel (dating to around 5,000, 3,000 and 2,500 years ago), which were believed to have contained alcoholic beverages (beer and mead), were found to contain yeast colonies that had survived over the millennia, providing the first direct biological evidence of yeast use in early cultures