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However, the gshF copy number increase didnt further improve GSH concentration in W303-1b/F, indicating that a reasonable rather than high copy number of gshF gene driven by GAP promoter is sufficient for the highest expression levels and synthetic capacity of GSH through one pathway is limited

This can increase sodium and water excretion and may slightly reduce circulating blood volume

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Blood samples from people with severe acne show low GSH and higher oxidative stress, a possible cause for frequent acne breakouts