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When muscle mass drops too much: Your metabolism slows down , so you burn fewer calories You lose strength, stability, and energy You may regain fat more easily after stopping the medication You increase your risk of long-term frailty and poor body composition The goal isnt just to lose weight its to lose fat while keeping (or gaining) strength

Diabetes Obesity Metab 2023;25(6):175868

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GF-TRIPLE later emerged as one of the experimental compounds used to study multi-receptor incretin signalling systems and complex metabolic regulatory networks