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Progressive, bilateral, or functionally impairing numbness requires GP assessment to identify reversible causes

Alberto Espay, a neurologist at the University of Cincinnati College of Medicine, said the key questions that remain are how do GLP-1s help protect the brain and by how much

doi: 10.1002/jobm.201700428 26 KanitsoraphanC.RattanawongP.CharoensriS.SenthongV

Given that glutaryllipoyl adducts form under conditions of glutarate excess on another TCA cycle ketoacid dehydrogenase, the PDHc 9 , we hypothesized that the major role of ABHD11 may be to reverse lipoyl glutarylation, maintaining TCA cycle integrity (Fig