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Chen, T., & Zhao, X

longer in tissue depots ROUTES Topical (cosmetic) Subcutaneous (research) Intradermal (research) MECHANISM OF ACTION Naturally occurring tripeptide Gly-His-Lys bound to a Cu ion

GHK-Cu and Photodamage-related Oxidative Stress Photodamage to tissues, including the skin, may involve the generation of reactive oxygen species (ROS), reactive nitrogen species (RNS), and reactive carbonyl species (RCS), which might lead to damage to proteins, DNA, and lipids

The study documented hair follicle-stimulating properties, with topical application resulting in increased follicle activity compared to controls (Uno & Kubo, 1992)