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After invasion into the host, mycobacteria induce NADPH oxidase 2 (NOX2) expression to generate superoxide radicals (O 2 ), which are then converted to more toxic hydrogen peroxide (H 2 O 2 ) by superoxide dismutase (SOD) and subsequently reduced to water and molecular oxygen by catalase [57, 58]

Ethics declarations Competing interests A.C.: AstraZeneca, Eli Lilly, Novo Nordisk, Roche Diagnostics, Sanofi Aventis

Lee YM, Lee KW, Park H

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity (Nature, 2014) Synonyms: 5-amino-1-methylquinolinium, SCHEMBL6403148, SCHEMBL9331979, CHEMBL4116828, ZMJBCEIHNOWCMC, UHFFFAOYSA-O