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5 Reactive oxygen species as oxidizing agents: impact on cysteine proteinases and cellular homeostasis It has long been established that disturbances in reactive oxygen species (ROS) regulation generate highly reactive cellular environments, profoundly influencing intracellular signaling pathways and contributing to oxidative stress

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Within the mitochondrial matrix, carnitine palmitoyltransferase II (CPT2) regenerates acyl-CoA from acylcarnitine, releasing free carnitine for recycling