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Chan School of Public Health, (2)University of Pennsylvania, (3)Massachusetts General Hospital Background: Patients with type 2 diabetes mellitus (T2DM) are at a great risk of liver cancers including hepatocellular carcinoma (HCC)

Damage to neuron structure and function is the primary cause, which ultimately results in the death of nerve cells in the human brain (588)

reported that KGN cells treated with DHEA exhibited ferroptosis characterized by decreased viability, inhibited GPX4 and SLC7A11 expression, increased ACSL4 expression, increased MDA levels and ROS accumulation, and increased lipid peroxidation

By revealing subtype-specific molecular and biological pathways, we aim to identify candidate biomarkers and elucidate the distinct molecular mechanisms that may contribute to the heterogeneous clinical trajectories of PD