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My only hesitation in accepting the hypothesis that obesity is a downstream effect of hypothalamic inflammation lies in the fact that, in metabolically healthy individuals, a normally functioning digestive system, a non-steatotic liver, nutrient-sensitive pancreas and intestine, insulin-sensitive adipose tissue, should mitigate, at least to some extent (though not completely), the negative effects of an unhealthy diet, until their compensatory capacity fails
However, if you are diagnosed with acute hepatitis C, your healthcare provider may initially observe your condition to see if the infection becomes chronic before deciding on treatment
GLP-1RA can be used in patients with hepatic impairment, without dose adjustments, although they have not been extensively studied in these circumstances (71)
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