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N Engl J Med 2016;375:18341844 [DOI] [PubMed] [Google Scholar] 25.Marso SP, Daniels GH, Brown-Frandsen K, et al

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[1] [2] Probiotics raised GLP-1 in preclinical studies

Other reported or anticipated side effects based on Phase 2 data and the known pharmacology of the drug class include: Injection site reactions redness, bruising, or mild discomfort at the site of subcutaneous injection Fatigue commonly associated with caloric restriction and rapid weight loss Headache reported with GLP-1 receptor agonists as a class Increased heart rate (tachycardia) a known class effect of GLP-1 receptor agonists