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When acylcarnitine levels are depleted, the mitochondria are effectively starved of their primary fuel source

Current serotonin medications are aimed at increasing central 5-HT neurotransmission in the brain, and there are no approved indications for manipulating peripheral 5-HT, though peripheral 5-HT synthesis is being considered as a potential target for developing pharmacological agents in some disorders ( We are not aware of prior studies reporting low S-5-HT in hypothyroidism or CFS

A compound naturally present in the body

As L-Carnitine acts as an activator of fatty acids in the body so that they can be properly burnt by the mitochondria and converted into energy, it is suggested that it be consumed before exercise in order to be effective and have positive effects