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Suppressing Gram-positive bacteria, including Clostridium , with antibiotics decreased the fecal DCA in this experiment ( Lactobacillus can increase the relative proportion of intestinal Clostridium and the production of SBAs (DCA and LCA) in rats fed in a high-cholesterol diet ( Lactobacillus decreased the absorption of BAs and increased the excretion of BAs in feces ( Bifidobacterium and the decrease in fecal LCA ( Bacteroidetes and high abundance of Erysipelotrichaceae indicate excessive SBAs in feces ( Methanogenic bacteria have been reported to deplete both trimethylamine (TMA) and TMAO ( Lactobacillus and Bifidobacterium ) significantly increased the TMAO levels ( Bacteroides lack the related genes, whereas these genes exist in the Firmicutes, Proteobacteria and Actinobacteria phyla ( Firmicutes ( Proteobacteria and Actinobacteria ( Bacteroidetes did not produce TMA, and Wang et al

2014 studies [38, 50] were excluded as they reported results for relevant interventions with only secondary comparators

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