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As such, the association with efficacy may be the result of enhanced trafficking of the protein within the cell that ultimately modulates the cell surface abundance of the receptor, rather than the result of alterations in the receptor protein structure that may influence ligand affinity

Potential side effects and tolerance are another critical consideration

While it can prevent thrombin from successfully going on to form blood clots, EGCGs main blood-thinning actions extend towards platelet deactivation, restoration of protein C levels and vasodilation