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Amylin replacement with pramlintide as an adjunct to insulin therapy in type 1 and type 2 diabetes mellitus: a physiological approach toward improved metabolic control Weyer C, et al

The latter are coated with enzyme-sensitive linkers or coatings that are responsive to MMPs and disintegrate to release the entrapped antioxidants at the tumour site

However, because of potential differences in vascular bed responses to vasoactive stimuli, it will be important to conduct additional studies in the future, in order to verify the absence of any effect of Protandim (or other NRF2 activators) on NO sensitivity in cerebral arteries (versus mesenteric arteries or other vessels)