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Who Should Wait GLP-1 may not be appropriate if you're pregnant or breastfeeding, have personal/family history of medullary thyroid cancer, have multiple endocrine neoplasia syndrome type 2, or have active gallbladder disease
Tirzepatide (Mounjaro, Zepbound) is a glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management and chronic weight management
One clinical study found that people who stopped semaglutide treatment regained two-thirds of the weight they lost on the drug
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