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And they activate the same downstream pathways in the liver, fat tissue, and pancreas

Brennan PJ, Brigl M, Brenner MB

Factors that extend the waiting period Several situations warrant waiting longer than the standard timeline: Postpartum hemorrhage or significant blood loss during delivery Preeclampsia or pregnancy-induced hypertension that has not fully resolved Active postpartum depression or anxiety that is not yet stabilized with treatment Difficulty establishing breastfeeding or low milk supply concerns Ongoing wound complications from C-section or perineal repair History of eating disorders, which GLP-1 appetite suppression could trigger Significant nutritional deficiencies identified in postpartum blood work, particularly iron deficiency anemia The American College of Obstetricians and Gynecologists has not yet issued specific guidelines on postpartum GLP-1 use, which means decisions are being made on a case-by-case basis between patients and their providers

Dehydration can cause headaches, fatigue, and constipation, all of which mimic or worsen GLP-1 side effects