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Unlike single-pathway medications, tirzepatide's dual mechanism compensates for the hormonal dysregulation that gallbladder removal creates

Published mechanisms include upregulation of growth hormone receptor expression, promotion of angiogenesis via VEGF pathway activation, modulation of the nitric oxide system, and interaction with the dopaminergic and serotonergic systems in neurological models

[DOI] [PMC free article] [PubMed] [Google Scholar] 71.Mailloux R.J

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