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The Financial Times calls Asprey a biohacker who takes self-quantification to the extreme of self-experimentation because he used techniques to upgrade his brain by 20 IQ points, lowered his biological age, and lost 45 kilograms (100 pounds) without using calories or exercise

Hence, it can exist in various states, depending on the local redox environment and the presence of oxidizing and reducing agents

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Conversely, a decline of NADPH/NADP + ratio induced by G6PD deficiency blocks the glucose-stimulated insulin secretion, triggering oxidative stress and beta-cell apoptosis [111, 112]