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In accordance with NICE guidance , management of restless legs syndrome involves identifying and treating underlying causes, addressing lifestyle factors, and considering specific treatments if symptoms are moderate to severe and significantly impact quality of life

Sulforaphane suppresses a accumulation and tau hyperphosphorylation in vascular cognitive impairment(VCI)

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The study excluded cross-over trials without washout period, those in critically ill patients, pregnant or breast-feeding women, multicomponent interventions and active control groups with tea or coffee