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More serious but less common risks include pancreatitis, gallbladder disease, acute kidney injury (usually secondary to dehydration from gastrointestinal symptoms), and diabetic retinopathy complications, particularly in patients with pre-existing retinopathy who experience rapid improvement in blood glucose

In the meta-analysis of this study, eight randomized controlled trials (RCTs) met the inclusion criteria, all of which examined the effects of coenzyme Q10 or DHEA on ART outcomes in DOR/POR patients (Xu et al., 2018

Reversible decreases in total sperm count and motility were noted with the use of 5ARIs, with a return to baseline parameters 24 months after discontinuation

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