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The above results could indicate that erastin and Fer-1 were able to activate intracellular reactive oxygen species production in Vero cells treated with erastin, while Fer-1 could inhibit this process at 12 hours but was less potent than erastin

Genome-wide chromatin immunoprecipitation profiling of Sox2 downstream targets in ESCs surprisingly showed that one-half of all Sox2/Oct/Nanog-bound genes represent CG-rich developmental TFs (Kim et al., 2008)

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