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The main difference is the level they act on

Pregnant or breastfeeding people, anyone with active cancer or a recent cancer history, anyone with a seizure disorder, children and teenagers, and anyone on prescription central nervous system medications should avoid Pinealon outside formal medical supervision

And the doctor who prescribed it would refute the lack of data, saying the absence of evidence is not evidence of absence, and that his patients are deriving substantial benefit without side effects

It does not replace the official medication guide, patient information leaflet, counseling from your pharmacist, or medical advice from your prescriber