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Juvenile and adult worms were carefully washed in phenol red free RPMI medium and subsequently incubated in phenol red free RPMI medium supplemented with 5.5 mM D-glucose, penicillin-streptomycin and 5% heat inactivated fetal bovine serum and at 37 C in a 5% CO 2 incubator overnight

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The first bottleneck is supply : damaged tissue needs fresh blood vessels to deliver oxygen, nutrients and repair signals

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