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[DOI] [PubMed] [Google Scholar] 8.Mohammed S.A.D., Hanxing L., Fang L., Algradi A.M., Alradhi M., Safi M., et al

Since 1959, phentermine has been prescribed as part of a comprehensive weight-loss program that includes proper diet, exercise, and lifestyle modifications

By binding with IGF-1, IGF-2, and insulin, IGF-1R activates downstream pathways including phosphoinositide 3 kinase (PI3K)/AKT and Ras/extracellular signal-regulated protein kinase (ERK) pathways, 1 two frequently activated pathways in colorectal cancer

Importantly, oxidative damage caused by the production of ROS has been linked to the etiology of different types of human cancer [23, 36]