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Recently, postzygotic mutations in beta-actin were reported to be associated with Becker nevus and Becker nevus syndrome (see below)

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In both in vitro and in vivo studies, Epitalon treatment is associated with increased TERT expression, elevated telomerase enzymatic activity (TRAP assay), and measurable preservation of telomere length as assessed by quantitative-FISH (Q-FISH) and Southern blotting of terminal restriction fragments (TRF)