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Methodologically akin to a retrospective cohort analysis, our study differs in that it emulates a target trial by prespecifying the protocol, aligning index date, and using propensity score matching to emulate randomization, thereby reducing immortal-time bias, improving transparency, and aligning real-world evidence generation with clinical trial standards

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I have a normal BMIcan I get a prescription for a weight loss drug?No, we do not treat new patients with normal BMI with weight loss pharmacotherapy, unless the patient shares outside records documenting previous obesity