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Dont overdesign

(3) When the researchers running the study measured the release of fatty acids and glycerol from radiolabeled triglycerides, they observed about a 4050% increase compared to the starting levels

In vitro assay designs that isolate GLP-1R and GIPR signalling from GCGR signalling for example, using receptor-selective antagonists are one methodological approach used to attribute observed effects to each receptor arm