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Autoimmune encephalitis, especially forms associated with N-methyl-D-aspartate (NMDA) receptor and voltage-gated potassium channel (VGKC) -complex autoantibodies, is characterized by sudden-onset neuropsychiatric symptoms, cognitive dysfunction, seizures, and altered consciousness
For example, nanodelivery systems have been proposed for DNase I, PAD4 inhibitors, or P-selectin/PSGL-1 blockers, thereby localizing therapy to sites of neutrophil activation and minimizing systemic side effects [98]