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In clinical trials, tirzepatide led to substantial average weight loss, with higher doses generally producing greater reductions when combined with lifestyle changes

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KO, n = 3 representative from 2 independent experiments, p = 0.0001) (c)

A mixture of ultrapure water (0.6 mL) and chloroform (1.5 mL) was added to the above mixture for homogenization in the dark for 2 h, after which 4 mL of a chloroformmethanol mixture containing 0.01% BHT was added, shaken for 20 min, and the extract collected