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GAT-1 maintains the homeostasis of inhibitory neuronal microcircuits, and its functional or expression abnormalities are closely associated with the development of various neurological disorders, including autism, schizophrenia, and epilepsy (42, 43)

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In silico modelling suggests that rs146558 is a nonsynonymous single nucleotide polymorphism that leads to disruption in protein function

269 In a randomized, controlled, crossover trial in 11 healthy people, taking a lemon balm extract providing 500 mg rosmarinic acid per day for seven days was found to be safe and tolerable