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227 Similarly, HRD1 suppresses IRE1-mediated ER stress responses by facilitating the degradation of unfolded proteins in Treg cells, maintaining Treg stability and function, suggesting that HRD1 controls the IRE1 pathway

63 This natural drug shows great therapeutic potential owing to its dual antiproliferative and apoptosis-inducing effects, its anti-inflammatory effect also suggests its potential to sensitize high-inflammatory cells to radiotherapy, which highlights its promise in osteosarcoma radiotherapy treatment

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