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Folate losses in the boiled pulses due to heating degradation and leaching depended on the pulse variety and ranged from 18% to 36%, with an average of 24%, compared to unprocessed ones 411

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Methionine alone cannot compensate for choline deficiency, and choline cannot bypass impaired SAMe synthesis if methionine is depleted

however, challenges such as delayed early diagnosis and intervention, poor efficacy of antidepressants, and numerous side effects make depression difficult to detect and treat (4, 6, 338)