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Complementing these studies, Guo et al

Most microglia (green) in the field immediately retract their ramified processes, funneling all available cell mass into single, phagocytotic processes at the glial limitans

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Baseline markers may include: Fasting glucose HbA1c Lipid panels Body composition measurements when available Without baseline measurements, it becomes difficult to determine whether metabolic changes are occurring or whether dose adjustments are producing meaningful effects