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By establishing a temporal framework for liver organoid development, this work facilitates the standardized application of iHLOs across drug screening, toxicology testing, and disease modeling

Franklin CC, Krejsa CM, Pierce RH, White CC, Fausto N, Kavanagh TJ

148 This is the central feature of the set-point model of cellular metallostasis since the relationship between the metal dissociation constant and the bioavailable metal concentration defines the sign on the conditional free energy of metal loading