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2.4.2 Definition of Analysis Sets and Statistical Analysis of Endpoints Pharmacokinetic, PD and safety assessments were based on all subjects who received one or more doses of trial product

In the present study, we carried forward these four ACs and tested whether the relationships with depression predicted from genomic data (negative with C2 and C3, and positive with C8 and C10) were expressed in actual phenotypes measured in a large cohort (N ~ 2500) with extensive clinical phenotyping

Moreover, the increased pressure in the stomach pushes against the lower esophageal sphincter (LES), causing acid to escape into the throat

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