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The study found that 2.2% of women became pregnant within six months of starting GLP-1 treatment with pregnancy rates highest among younger women with diabetes, and among women without diabetes in their early thirties

Conclusion: This study revealed a critical role of CRL3 in hepatic metabolic regulation and identified NRF2-mediated NADH-reductive stress as a previously unrecognized downstream effector modulating the development of hepatic steatosis

The group furthermore showed that cisplatin treatment increased Nox3 expression in the cochlea predominantly at the basal turn and in the supporting cells