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Slow titration of dose can help, as can dietary adjustments. The recent mast cell paper suggested: significantly lower doses of GLP-1RAs than presently used as starting doses for T2DM and obesity therapy might be sufficient, and even optimal, for MCAS

Intriguingly, a recent report rebutted that a myostatin deficiency is beneficial for mdx mice and also excluded a direct effect of myostatin on satellite cells [54]